Setrakian and Fet battle for possession of the Occido Lumen, and gain a surprising new ally. A massive attack imperils Eph, Nora, and Zack's escape from New York. -- New York City is rapidly falling to an evil epidemic, and its citizens must fight or die. Dr. Ephraim Goodweather and his unlikely allies concentrate on creating a weapon to wipe out the strigoi, but the Master is out for revenge, sending new and even more terrifying breeds of bloodthirsty creatures after his team. They must find a way to defeat him before the transformation becomes irreparable - and before they become monsters themselves.