Tensions rise between Dominick (Mark Ruffalo) and his live-in girlfriend, Joy (Imogen Poots), as the media begins to take an interest in Thomas' (Mark Ruffalo) case. In his attempt to have Thomas released from the Hatch forensic institute for the criminally insane, Dominick finds a potential ally in social worker Lisa Sheffer (Rosie O'Donnell), but learns that helping his brother may be more difficult than he thought.
Dominick clashes with Thomas' new psychiatrist, Dr. Patel (Archie Panjabi), as she begins to probe into his past. We learn about the shocking tragedy that triggered the dissolution of Dominick's marriage to Dessa (Kathryn Hahn).
