When the surgical interns are given an impromptu medical quiz with a chance to assist in surgery as the prize, only Emily (Mamie Gummer) and Cassandra (Aja Naomi King) are left standing. After an STD outbreak at a local high school becomes an issue, Emily reluctantly agrees to speak to a group of high school girls about safe sex. Meanwhile, Emily continues to try to forget about her feelings for Will (Justin Hartley), but finds the task easier said than done.