Annie, Jimmy and Luke are in hot pursuit of a fugitive when he leaps out a window onto a neighboring rooftop. Annie fearlessly jumps after him, and with a little help from Jimmy, manages to nab him. At H.E.A.T., Jimmy tells Annie that he's going on a cruise with Natalie. Annie teases him playfully while she repairs her boots; they got damaged during her last chase. Marco enters with news on Karen Nelson, a Canadian fugitive who's been spotted in Texas. Before fleeing Canada, she robbed her husband's bank and then killed him when he found out. Across town, Karen and a pretty blond accomplice flip a coin and recite, "For better or worse, I'll be there first." The two women then break into a woman's home and demand that she call her husband Vincent.
At H.E.A.T., Marco explains that Canadian authorities are asking the Marshals to perform a "discreet locate" on Karen. That means that the Marshals have to find Karen, photograph her, and verify her identity with Canadian officials. Only then can Annie and her gang get a warrant. Annie and her team find Karen and her blond accomplice at a seedy bar. Luke and Jimmy flirt with them and before long, Jimmy's able to snap a picture of the ladies. Jimmy even manages to snag a beer bottle with Karen's prints on it. Marco runs Karen's prints and says they match a fugitive who robbed a bank in Houston. Looks like Karen's back to her old tricks and since it's on American soil, Annie can take her down.
Daisy tells Annie more about Karen's robbery. Turns out she held a bank teller's wife and son hostage in order to get access to the bank. Authorities have tracked down Karen's Mustang to an apartment building. The chase is on! Annie breaks into Karen's apartment but it's empty. Luke and Jimmy find candy wrappers and recall that Karen's accomplice loved sucking on lollipops. They find shoes of different sizes – proof that Karen and her sidekick both stayed there – and a strand of hair from a wig. Next Annie and her team look at surveillance footage. They see Karen that Karen drove off in a minivan hours before.
At H.E.A.T., Annie talks to Vincent's wife. She doesn't have many clues but remembers hearing Karen and her friend say, "for better or worse, I'll be there first" before flipping a coin. Karen lost and therefore had to retrieve the cash while her friend waited. Karen was the one in charge while her pal seemed to just be along for the ride. While Karen and her accomplice hold another family hostage, Annie attempts to profile Karen Nelson. Karen killed her husband, stole his money, and left Canada for the U.S. Now Karen's found a sidekick and together they've been attacking bank tellers at small regional banks.
At a rundown hotel, Annie talks to Mr. Nelson, Karen's father. He's a sad man with a weathered face who blames himself for Karen's bad behavior. Annie tells Mr. Nelson to call her if he hears from Karen. In Carlsbad, New Mexico, Karen kills a bank teller when he won't hand over the cash. Blood splatters the car's window while his family screams inside. At a motel, Annie tells Daisy about Karen's grisly back story: Karen's dad beat her mother. Karen's mother committed suicide and Karen found the body. All this talk of Karen's family life makes Annie and Daisy realize how little they know about each other. Daisy reveals that she has five brothers. Annie shares that her middle name is Nolan.
In Carlsbad, Karen and her sidekick look for a rental car. They flirt with an employee on the car lot and convince him to go on a little joyride in one of his courtesy vans. Later, Annie tracks this van to Roswell, New Mexico. Unaware that they're being followed, Karen and her gorgeous sidekick have an argument. Karen wants to save the stolen money, while her accomplice wants to blow it all and have some fun. Karen's accomplice – who we finally learn is named Ivy – meets up with her husband Neil in a motel room. Ivy says she wants to reunite with him and she's sorry she disappeared. Karen interrupts the romantic moment and shoots Neil dead. When Ivy protests, Karen says she killed Neil because he was calling the cops.
At the motel, Annie and her team find Neil's dead body and Ivy's stolen van. Karen and Ivy have left in Neil's Camaro and should be long gone by now. Annie guesses that Karen lured Ivy into a life of crime after meeting her in Santa Rosa, New Mexico. Daisy finds Neil's cell phone; Karen was right, Neil was calling the cops and ratting on her. Neil's cell accidentally recorded his entire conversation with Karen. Daisy says she'll listen to the recording for clues. Annie guesses that Karen and Ivy are heading to Ivy's home in Santa Rosa. Now that Neil's dead, their home might be the perfect hiding place. On the way to Santa Rosa, Annie and Daisy listen to Neil's cell recording. They hear Karen convincing Ivy that Neil was a bad man and saying that she loves Ivy.
Annie and Daisy check out Ivy's spotless house. Annie guesses that Neil was a control freak who preferred his car to his wife. Meanwhile, Ivy drives Neil's beloved Camaro into a lake. She and Karen get drunk and laugh about their newfound freedom. Suddenly the talk gets serious. Ivy lost the coin toss and as a result, Karen punches Ivy in the jaw! While Annie and Daisy search Ivy's home, Daisy reveals that her middle name is Gladys. Annie laughs and promises to reveal another secret once they're back at H.E.A.T. Annie notices a framed picture of Ivy wearing a turtleneck in the middle of summer. Annie correctly theorizes that Ivy was hiding bruises. Neil clearly used to beat her! Annie guesses that the two women might be hiding out at a women's shelter.
After sending photos of Karen and Ivy to women's shelters in Arizona, Annie finds a shelter in Flagstaff that says the women have checked in. At the Flagstaff shelter, Karen notices an employee looking at her strangely. Karen gets a hunch that the Marshals are on their way and hides in her room with Ivy. They flip a coin and Karen wins. The Marshals arrive at the shelter and find Ivy holding a woman hostage. Annie calmly tells Ivy to drop the knife and save herself. Clearly in over her head, Ivy gives in and allows her hostage to go free. She won't, however, reveal where Karen's headed. On a country road, Karen hitches a ride with an unsuspecting truck driver.
At the police station, Annie interrogates Ivy. Annie tells Ivy that he coin tosses were rigged; the coin had "heads" on both sides. To retaliate against Karen, Ivy reveals that "for better or worse, I'll be there first" referred to a place Karen loved to visit before her mom died. Annie smiles; she knows just the place. Annie tracks Karen down to an idyllic cabin. Karen makes a run for it until she reaches the edge of a cliff. Annie begs Karen to stop running. Annie reveals that she's spoken to Karen's dad and he says he's sorry. Karen jumps off the cliff, but Annie and Jimmy grab her and pull her to safety and arrest her. To celebrate, Annie and Daisy get manicures. Annie reveals three secrets: she's got pretty feet; she always wears her favorite pair of boots because her father gave them to her; and she has no idea where her father is.