In the year 2025, a world where primal instincts dictate societal hierarchy, ABO Desire plunges viewers into a volatile romance that defies biological fate. The series follows Jae-won, a powerful and cold Alpha heir to a corporate empire, who is shocked to discover his destined mate is not a compatible Omega, but the fiercely independent Beta, Soo-hyun. Soo-hyun, a brilliant and ambitious architect, has spent her life defying the system that devalues Betas, and she wants nothing to do with an Alpha who sees her as a biological anomaly. Their explosive chemistry is undeniable, yet their incompatible designations create a central conflict that threatens both their careers and their very identities. As Jae-won struggles to control his possessive Alpha nature and Soo-hyun fights to maintain her hard-won autonomy, they must navigate a world of corporate intrigue, family pressure, and societal prejudice. The show delivers a tense, passionate atmosphere, exploring whether love can truly conquer the most fundamental of instincts.