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Wilson Cruz of "My So-Called Life" makes a return to ABC by guest starring on "Grey's Anatomy". The first look of him as a groom whose bride got a freak accident on their wedding day has been released. It looks like Callie would be the attending doctor and do the talking.

Cruz will appear in the January 13 episode where another blast from the past by the name of Scott Foley is also in. Some spoilers have come out about this episode, including the fact that Callie will announce a big news. Reports say she is not giving Arizona a kind welcome after her surprise return from Africa.

The synopsis says, "Arizona seeks Mark's advice as she tries to reconcile with Callie, who has big news of her own; Teddy must make a key decision for Henry during his surgery; and on the same day the residents receive a new crop of interns, the Chief announces he is looking for a new Chief Resident."

Also TV Guide reported that Derek will begin his Alzheimer trials, but he's still hot and cold about including Meredith in the team. And then he chooses another researcher which leads to a huge confrontation with his wife.