Jane is a career-driven 30 year-old surviving singleton in New York City. Between her unsociable working hours as a forensic pathologist, pressure from her devoutly Jewish mother to find the right man, and a series of fleeting flings, she has yet to commit to a long-term relationship. On her 30th birthday, she decides to just that.

When she meets Ted, they hit it off. But soon as bodies come into the morgue, she can't help but notice that people who have recently been rude to her are dying one by one. She wonders if Ted might be a serial killer and questions whether being in a loving relationship with a serial killer is worse than going back to being a single woman in her thirties.