Set amidst the appealing locales of Thailand, "Ready" revolves around Prem (Salman Khan), the sole heir to a sprawling empire owned by his father and uncles. Prem's father desires that he gets married and settles down, though Prem intends to enjoy his single status to the fullest.

Enter Sanjana (Asin), an orphan whose greedy uncles are constantly conspiring to acquire her property.

In a dramatic twist of Fate, the eternal bachelor Prem falls in love with Sanjana, and is ready for marriage owing to a case of mistaken identity Sanjana has just returned to India to live with her feuding uncles, who have their own devious plans for her marriage, in order for each to take over her inheritance.

Prem, along with his entire family, take it upon themselves to ensure that Prem and Sanjana are united. What ensues is a series of hilarious events, with everyone taking on various identities in order to fool the uncles with Prem of course masterminding the entire charade.