Based on the novel "Flora & Ulysses: The Illuminated Adventures" by Kate DiCamillo, the film is about 10-year-old Flora (Matilda Lawler), an avid comic book fan and a self-avowed cynic, whose parents have recently separated. After rescuing a squirrel she names Ulysses, Flora is amazed to discover he possesses unique superhero powers, which take them on an adventure of humorous complications that ultimately change Flora's life--and her outlook--forever.