Dead on Arrival stars Billy Flynn as Sam Collins, a sales rep who visits a small town in Louisiana to close the business deal of a lifetime. He finds himself in a dark world of corruption and murder when he is poisoned with no antidote to save his life.

Desperate for answers, with only 24 hours to live, Sam turns to local girl Jesse (Christa B. Allen). On the run, caught in a deadly vertigo with no one to trust, Sam and Jesse find themselves running from police detectives, the mob and a dirty sheriff who wants them dead.