In an attempt to bring some normalcy to his increasingly chaotic life, Dr. Charlie Harris (Michael Shanks) decides to go the entire day without using his "special abilities". His vow is put to the test, however, when a superstitious farmer is admitted with a myriad of injuries, forcing Charlie to re-evaluate his decision.
Meanwhile, fearing for Dr. Dana Kinney's (Wendy Crewson) outlook when she is confined to the hospital by her oncologist, Dr. Alex Reid (Erica Durance) organizes a road trip north to Dana's cabin for the annual cottage festival. With Dr. Dawn Bell's (Michelle Nolden) college roommate Reba's (Kristen Thomson) life on the line after being bitten by a spider, it is Dr. Zach Miller (Benjamin Ayres) who helps keep the situation under control.