Skylar Adams, an Alpha-powered, super-inventor, is working in her loft laboratory when her robotic wasp detects soldiers approaching. By the time the soldiers get into her place, Skylar is perched on a roof across the street and, with the press of a button she detonates a bomb, preventing them from following her any further.
The following morning Bill and his wife Jeannie have a fight about having children-Bill is reluctant to move forward because he's worried that his children might turn out to be Alphas, too. Across town, Gary's mother tells Dr. Rosen that Gary has to stay home because he's sick but the reality is she doesn't want Gary to work for Dr. Rosen any more-she thinks the work they do is too dangerous. Meanwhile, at the office, Dr. Rosen notices the sexual tension between Hicks and Nina and wants to make sure they don't get romantically involved.
When Agent Sullivan finds out about the incident with Skylar, the team heads over to her loft to investigate. Thanks to Rachel's abilities, the team gets a lead on Skylar's whereabouts and tracks her down at a farmer's market in Brooklyn. Somehow, however, the soldiers have gotten to the farmer's market first. With Skylar in danger, the team jumps into action and is able, just barely, to save her. Not that she appreciates it.
Back at headquarters, Skylar seems ungrateful but her instincts prove correct: Even though Dr. Rosen reassures her that the team will protect her, Agent Sullivan soon shows up with orders to keep Skylar in "protective custody" at Binghamton while she creates weapons for the Department of Defense. Before Agent Clay and the rest of the Binghamton team show up, the soldiers who have been following Skylar appear with their guns at the ready. In a dangerous standoff, badges are drawn and it turns out that the soldiers are NSA agents. It seems that Skylar has been freelancing for the NSA and they have suspected her of selling military secrets via a complex mathematical algorithm.
Using her impressive inventing skills, Skylar builds a machine to incapacitate all of the people chasing her and seeks out the help of Nina, the one person she thinks she can trust. Nina helps Skylar blindly, hoping that her trust won't be betrayed. Their first stop? To kill B.O.B., the machine Sklylar built for the NSA to track anyone and everyone in the world.
With Gary's unexpected assistance, the team finds out that Skylar has been protecting her mathematically gifted daughter Zoe all along. Somehow, Skylar's Alpha abilities have been passed on to her daughter in a remarkable way and Skylar has been trying to prevent her from becoming a human guinea pig. Making a judgment call that he knows could land him in hot water, Dr. Rosen allows Skylar and her daughter to escape.
Agents Clay and Sullivan don't buy the story Dr. Rosen's later tells them but they have no choice but to accept it. For now.