Betty gets to run her own Mode photo shoot at the United Nations to promote their anti-malaria initiative, "Nothing but Nets," but her big opportunity becomes a baptism by fire when Daniel's neediness takes its toll, and Matt openly demoralizes her. Meanwhile, Amanda does some soul-searching when she bonds with Daniel's new temp, Helen (Kristen Johnston), a career receptionist as fabulous as Amanda is. Wili makes it her personal mission to protect a loved one, and Hilda reaches out to Marc to figure out how to help Justin.