While his father (John Schneider) is awaiting surgery, Clark (Tom Welling) befriends a young boy, Garrett (guest star James Kirk), whose brother Vince (guest star Tahmoh Penikett) just died from liver failure. However, everyone is shocked when Vince shows up at the hospital alive and seemingly well - until his liver starts failing again. In a desperate attempt to keep his brother alive, Garrett straps a Kryptonite bomb to himself and demands that Vince be given Jonathan's liver or he will blow up the building.