Tempers flare as Dev's med school rival arrives at the hospital; Alex puts her job in jeopardy to help save the life of an at-risk youth.
Trying to move on from his breakup with Dr. Alex Reid (Erica Durance), Dr. Charlie Harris (Michael Shanks) is focused on work. Faced with a patient who was thrown off a horse while re-enacting the War of 1812, Charlie channels all his energy into saving the man's arm. Meanwhile, Alex discovers Dr. Manny Palmer (Jarod Joseph, ONCE UPON A TIME) is going offsite to help a teenage runaway and makes the impulsive decision to join him. After bringing the girl back to the hospital and operating on her in secret, Alex faces an interrogation from Dr. Dawn Bell (Michelle Nolden).
Tempers flare when an old nemesis of Dr. Dev Sekera's (Dejan Loyola) from medical school arrives at Hope Zion. After Dev makes an uneasy truce with Dr. Billy Scott (Greg Calderone, HEROES REBORN), the pair struggle to revive a patient who has been frozen solid.