Dr. Alex Reid (Erica Durance) returns to work, arriving at Hope Zion Hospital with a car crash victim she encountered en route, and she's forced to play nice with new General Surgeon on call, Dr. Patrick Curtis (Max Bennett, Anna Karenina). The day gets even more chaotic when Alex is called away to treat Ted Crenshaw (Travis Milne), a convicted murderer brought in for emergency treatment. Meanwhile, Dr. Charlie Harris (Michael Shanks) begins to confront his feelings about the paternity of Alex's child, all while juggling an insistent Dr. Shahir Hamza (Huse Madhavji) who is looking for backup on his proposal for a new Alzheimer's study. In the ER, Dr. Zach Miller's (Benjamin Ayres) patient is admitted with symptoms mirroring those of Ebola -- putting himself and Dr. Maggie Lin (Julia Taylor Ross) at risk of exposure to the deadly virus.