A mysterious object plummets to Earth, sending out a shock wave that causes five strangers to perish, only to miraculously come back to life moments later. The group includes Vera (Shantel VanSanten), a struggling radio-astronomer searching for her missing son; Erin (Sofia Black-D'Elia), a young mother desperate to protect her seven year old daughter (guest star Madison Dellamea) from an abusive ex-husband (guest star Lane Garrison); Peter (Joel Courtney), a troubled high school student; Raul (JD Pardo), a federal agent looking to escape his dangerous and violent undercover assignment; and Joshua (Jon Fletcher), a charismatic second-generation televangelist. Most mysterious of all is the figure known only as The Man (Diogo Morgado), who offers Vera the one thing she wants most in life - if she will help him with one morally complicated task which puts her on a collision course with Rose (Anna Diop), a nurse who has been in a coma for seven years. Drawn together by fate and biblical prophecy, the "Messengers" soon learn they have supernatural gifts that might be the only hope for preventing the impending Rapture.