Jane frantically searches for Owen, who went missing after seeing her kiss Grayson just before their wedding. Luke tells Jane that "Old Jane" is back on earth and could be in anyone's body, even Owen's. Jane represents a desperate father trying to save his eight year old son who's fighting T-cell Lymphoma when his drug treatment is abruptly terminated by a pharmaceutical company. Meanwhile, Kim takes on the case of a woman whose ex-boyfriend posted nude photos of her on website devoted to ex-girlfriend revenge. Luke is reprimanded for mishandling Jane and gets replaced. Finally, Jane gets an unexpected visitor.