Larry learns the ups and downs of dating the disabled when he picks up Denise, prior to realizing she is wheelchair-bound. While sex and stairs pose a challenge, handicapped parking, special treatment at restaurants and being reconsidered by friends and acquaintances in a more positive light strike Larry as a plus. Meanwhile, a run-in with Rosie O'Donnell over a lunch tab and an unfortunate chain of events with his Blackberry converge to bring an end to Larry's handicapped dating.