Skye (Jessica Lucas) collapses the morning after the "Cult" fan party, suffering a serious reaction to the drug she was slipped. The doctors urge Jeff (Matt Davis) to locate a sample of the drug so they can find a way to reverse its effects in order to save Skye's life. Detective Sakelik (guest star Aisha Hinds "Weeds") arrives at the hospital but refuses to help. Jeff suspects that the drug might be hidden at her place so he takes matters into his own hands. Meanwhile, inside Skye's hallucinogenic state, Billy (Robert Knepper), Kelly (Alona Tal) and Skye's father Quentin (guest star Obba Babatunde) encourage Skye to give up and stop searching for the truth.