In the Season 5 opener, Michael Westen has been quite busy. Armed with a list of people who have burned him, Michael and his new CIA handler, Max, have dismantled the organization that ruined his life. Now only one man remains: John Kessler.

After learning the location of Kessler's heavily guarded compound, Michael is joined by Fiona and Sam on a CIA mission to Venezuela. If Kessler is captured, Michael can finally lift his burn notice and start rebuilding his life. But when the CIA rendition goes awry, it's up to Michael to complete the mission using "unorthodox" methods that have kept him alive for the last four years.