When a body wearing a gold bracelet is discovered in the abandoned ruins of a closed chain bookstore, the Jeffersonian team investigate. The victim is a female in her early twenties. Ripped fingernails indicate a struggle, and Hodgins deduces from the presence of brown recluse spider webbing and eggs on the body that she's been dead for about seven days. A fractured coccyx shows the victim rode horses frequently in an English saddle. She is identified as Mia Ferrara, 22, an affluent school teacher who taught in an underperforming school district in a rough neighborhood.
Caroline Julian takes a personal interest in seeing the case solved discreetly; she's on the board of United Teaching Fellows, the organization for which Mia taught, and worries that if word gets out that inner-city teaching is too dangerous, the program could suffer, and the underprivileged kids they serve will have to fight like she did to get a decent education. Suspects include Mia's not-so-wealthy musician boyfriend who reported her missing the previous Sunday, as well as the principal, fellow teachers, employees and students - and guardians of the students - at the school where she taught... and was much loved.
Meanwhile, Brennan's publisher encourages her to join Twitter to help grow her fan base, and "squintern" Jessica Warren teaches Brennan some tricks to master the Twitter-verse, skills Brennan enthusiastically puts to use.