Harry Wilson (Rob Estes, "Women's Murder Club"), new principal of West Beverly Hills High School, returns from Kansas to his childhood home of Beverly Hills with his wife Debbie (Lori Loughlin, "In Case of Emergency"), their daughter Annie (Shenae Grimes, "Degrassi: The Next Generation") and adopted son Dixon, (Tristan Wilds, "The Wire") to care for Harry's mother, former television star Tabitha Wilson (Jessica Walter, "Arrested Development"). On their first day at West Bev, Annie and Dixon encounter Ethan (Dustin Milligan, "Runaway"), the star lacrosse player she met a few summers ago; Naomi (AnnaLynne McCord, "Nip/Tuck"), the spoiled rich girl whose sole focus is her Sweet Sixteen party; Silver (Jessica Stroup, "Prom Night"), the free-spirited girl who later gossips about Annie on her blog, and Navid (Michael Steger, "Criminal Minds"), editor of Blaze News. When Naomi fails to complete an assignment, English teacher Ryan Matthews (Ryan Eggold, "Dirt") and guidance counselor Kelly Taylor (special guest star Jennie Garth, "Beverly Hills, 90210"), bring the problem to Harry, who quickly realizes that keeping secrets about his past is going to be impossible.
Dixon impresses his peers when he tries out for the lacrosse team, but has to deal with jealous teammates who will stop at nothing to sabotage him. Annie misses the deadline to audition for the spring musical but sparks fly when she meets the leading actor Ty (guest star Adam Gregory), one of the most popular students on campus. Ty impresses Annie by flying her to San Francisco for dinner in his private jet, but Annie fails to mention her plans to her parents. Special guest star Shannen Doherty reprises her role as Brenda Walsh.