The twenty-first century is the era of the brain, and this show will be riding that wave on the cutting edge of medicine. The brain is the source of everything -- from whom we love to how we act and feel. It is the ultimate mystery, which is why doctors call it, the "black box." Catherine and the staff of "The Cube" will constantly be challenged by cases never seen before on television. The patients have rare, highly visual, often hallucinogenic and startling conditions, which we will see through their eyes as Catherine diagnoses and treats them.