One question after another have been shot on whether Katherine Heigl and T.R. Knight will quit "Grey's Anatomy" or not, but never on the possibility of Patrick Dempsey leaving. The TV world is made rive when ABC released a synopsis for the March episode, where McDreamy comes to a decision that he wants to "quit".
Derek had made a questionable call when treating his pregnant patient which led to an unsuccessful result in the last week's episode. The husband of the patient goes on rampant and calls him a murderer, which leads to Derek rethinking that he has more failed cases than the successful ones.
In the next episode called "I Will Follow You Into the Dark", after learning at a deposition that more of his patients have died than survived, Derek decides to quit, even as Meredith refuses to give up on him. This subsequently brings two possibilities. Derek can either take a stance of his decision and leave the show or listen to Meredith and stay.
It leans to the latter however, since there has been no announcement from ABC regarding the exit and the fact McDreamy is such a big part of the show for five seasons. Moreover, E! Online quotes an insider, "[Derek] may be 'quitting' but [he is] definitely not leaving the show. [Dempsey] doesn't want to leave, and they wouldn't let him go anyway."
The show is taking a two weeks break and will return on March 12. Also in the episode, Bailey and the Chief continue to bicker over her peds fellowship - until Adele steps in to mediate - and Izzie's interns discover something unsettling on a "patient x," unaware that the charts they're looking at are actually Izzie's.