Izzie has a series of flashbacks of her dead fiance when a patient is treated for similar illness in the new 'Grey's Anatomy'.
The past comes back to haunt Izzie in the new "Grey's Anatomy". The 5.07 episode of the show will see Izzie being tormented when a new patient has similar sickness to her late fiance, Denny Duquette who died on the operation table after a failed heart transplant, and the fact that she is in charge of the case, affects her emotional state.
Meanwhile, the Chief announces to the residents that a solo surgery will be awarded, and the news sends them into a competitive frenzy. Meanwhile Derek turns to Bailey for advice when he feels Cristina is interfering in his relationship with Meredith, and Erica discovers a shocking connection between one of her surgical residents and a longtime patient.
It was previously hinted by EW's Michael Ausiello that Jeffrey Dean Morgan who portrays Denny will be back on the show for the November 6 episode. It wasn't clear whether he will come back as mere flashbacks or in a new scene but it was said that Izzie suffers a brain tumor which makes her able to communicate with the dead, meaning if it's true then he would have shot some new scenes.