Seems it is very possible to have Special Agent Fox Mulder and Dana Scully back on the big screen if looking on the good tidbit David Duchovny has brought in.
As reported by IESB.net, Duchovny told the press this week that he and co-star Gillian Anderson are in final talks to reprise the roles for the sequel to 1998's hit "The X Files", the first film adaptation of widely popular TV series of the same name. The actor was even confident that a deal would probably reached by the end of the week, with filming to commence next year.
While remarking that the entire story of the project is currently under development, Duchovny did confirm that the film would be a supernatural thriller while hinting that it would likely to follow up on the core stories of both the series and the movie. Since not much is known about the picture, keep staying with this site for further details then.