Investigated and pursued for decades by the FBI, the aging crime boss Meyer Lansky (Harvey Keitel) is now living in quiet anonymity in Miami Beach. When Lansky enlists a young journalist named David Stone (Sam Worthington) to tell his story, the Feds use him as a pawn to track down the hundreds of millions of dollars that Lansky has been suspected of stashing away for over half a century. As Lansky spins his dizzying tale, Stone finds himself caught in the middle of a game of cat and mouse, uncovering the hidden truth about the life of the notorious boss of Murder Inc. and the National Crime Syndicate.