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Viola Davis will face off Zoe Saldana in winning the Best Actress title, while Don Cheadle and Idris Elba will compete against each other in the Best Actor category.
'The Help' brings Octavia Spencer to win Best Supporting Actress kudo, 'A Separation' claims Best Foreign Language Film award, while 'The Girl with the Dragon Tattoo' wins Best Film Editing prize.
The civil-rights era drama bags the Outstanding Motion Picture award while bringing its actresses Viola Davis and Octavia Spencer to win the Outstanding Actress and Supporting Actress respectively.
Due to recent changes to the rules of the coveted category, nine movies including 'The Artist' and 'Hugo' are eligible to enter the list.
The civil-rights era drama leads the nominations by collecting eight nods, while the indie drama and the comedy film grab multiple noms, including from the Outstanding Motion Picture category.
In addition to the three feature films, the 18th annual Screen Actors Guild Awards picks 'Midnight in Paris' and 'The Descendants' as the contenders for the Outstanding Performance by a Cast.
The Emma Stone-starring drama raked in an estimated $19 million over the four-day holiday frame, while 'Spy Kids 4' climbed one spot at the chart with additional $1.8 million on the fourth day.
The Tate Taylor-directed drama secures the top spot for the third week in a row, holding off such newcomers as 'The Debt' and 'Apollo 18' from taking the crown.
Though reigning supreme, the Tate Taylor-directed drama only grossed $14.5 million as a result of Hurricane Irene disaster that affected the ticket sales in U.S. theaters.
Although some theater chains like AMC, Regal, and Clearview Cinemas are closing, the three-week-old drama does better than newcomers.
The drama starring Emma Stone rules the chart in its second week, while 'Spy Kids 4', 'Conan the Barbarian', 'Fright Night' and 'One Day' do not meet the expectations in their first week.
In the newly-released video, Stone's character goes deeper to address the racial lines laid between Mississippi maids and their employers by proposing a plan.