"After Louie" follows Sam (Alan Cumming), an artist and activist who lived through the early years of HIV/AIDS - a man scarred and still struggling with survivor's guilt. Cemented into an oppressive past, he is bewildered by a younger generation of carefree gay men with their uninhibited use of social media, sexting, and seeming political indifference.

But when he meets the seductive young Braeden (Zachary Booth) at a bar late one night, their pants quickly come down and, eventually, so does Sam's ossified guard. As the pair become increasingly intimate, an intergenerational relationship blossoms between them-one capable of reawakening Sam's artistic soul and reviving his wilted heart.