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The music video sees the 'Follow the Leader' duo, Breezy and the Auto-Tune king busting a move and mingling with hot-looking ladies.
Premio Lo Nuestro Latin Music Awards which was held in Miami on February 17 also honored newcomer Prince Royce and World Icon, Ricky Martin.
Alicia Keys teams up with Alejandro Sanz, Calle 13 make a duet with Ruben Blades, and Laura Pausini has a solo performance at the Latin Grammys.
In addition, Jonas Brothers win Best International Pop Artist and their youngest member, Nick Jonas, gets Fashionista Award.
Beyonce Knowles and Lady GaGa get nine nominations at this year's MTV Video Music Awards, while Britney Spears follows with seven nods.
Wisin and Yandel take 50 Cent to an abandoned building and sing 'Mujeres en el Club' with him in a music video for the song.