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The exiting 'Fashion Police' co-host also expresses her regret for taking the job, saying, 'I probably shouldn't have taken the gig.'
Griffin says she is surprised by the various reactions over her 'Fashion Police' exit, and appreciates all the supports she receives via Twitter.
Sources say there had been numerous issues including an alleged feud between Griffin and co-host Brad Goreski that prompted the show's producers to hold discussions about firing Griffin.
Hollywood stars like Lena Dunham, Chelsea Handler, Jane Lynch, and Josh Groban cheer on Griffin after she announced her departure from the E! show.
The actress-comedienne says in a tweet she quits the show because she thinks it is too mean-spirited.
The new 'Fashion Police' critic is also questioned about Kelly Osbourne's departure which was announced on the heels of the drama.
Griffin also pays tribute to her friend Joan Rivers by wearing the late comedian's fur coat, while Cooper mocks Piers Morgan during CNN's New Year's Eve telecast.
New host Griffin gives a first taste of her witty remarks as she appears with Brad Goreski, Kelly Osbourne, and Giuliana Rancic in the commercial.
Griffin is tapped as Joan Rivers' replacement, and TV personality Brad Goreski joins the E! show to replace co-host George Kotsiopoulos.
Griffin will be joined by Giuliana Rancic, Kelly Osbourne and Melissa Rivers on the E! show that will no longer be a weekly series.
In addition to the 'Imitation Game' actor, Anderson Cooper, Christina Hendricks and Sheryl Crow pose for cameras on the red carpet.
Sources, however, say that Griffin is unlikely to replace Joan Rivers on the E! show after she 'tested poorly' for the show.
Griffin, however, is unsure about accepting the gig, saying, 'I don't know if the situation is correct at this time for me or right for me at this time.'
The 'Kathy Griffin: My Life on the D-List' star is reportedly among male and female comedians considered to replace the late comedienne on the E! show.
The comedienne reveals she was interested in Craig Ferguson's spot that now belongs to James Corden, but an exec told her at the time, 'They're not considering females at this time.'