(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Best Actress in Comedy (Year in Television) | Ugly Betty (2006) (TV) | - |
| 2008 | W | - | Ugly Betty (2006) (TV) | - |
| 2007 | W | Outstanding Actress in a Television Series, Mini-Series, or TV Movie | Ugly Betty (2006) (TV) | - |
| 2006 | N | Outstanding Actress in a Motion Picture | The Sisterhood of the Traveling Pants (2005) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Outstanding Lead Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2007 | W | Outstanding Lead Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2007 | W | Best Actress | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Best Performance by an Actress in a Television Series - Musical or Comedy | Ugly Betty (2006) (TV) | - |
| 2008 | N | Best Performance by an Actress in a Television Series - Musical or Comedy | Ugly Betty (2006) (TV) | - |
| 2007 | W | Best Performance by an Actress in a Television Series - Musical or Comedy | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | W | Outstanding Female Actor in a Leading Role in a Comedy or Musical | Superstore (2015) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2014 | N | Best Actress/Supporting Actress - Feature Film | Cesar Chavez (2014) | - |
| 2010 | W | Best Actress - Feature Film | The Dry Land (2010) | - |
| 2010 | N | Best Actress - Television | Ugly Betty (2006) (TV) | - |
| 2010 | N | Best Actress - Feature Film | Our Family Wedding (2010) | - |
| 2009 | W | Best Actress - Television | Ugly Betty (2006) (TV) | - |
| 2007 | W | Best Actress - Television | Ugly Betty (2006) (TV) | - |
| 2006 | W | Best Actress | The Sisterhood of the Traveling Pants (2005) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | N | Best Debut Performance | Real Women Have Curves (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Outstanding Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2009 | N | Outstanding Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2008 | W | Outstanding Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2007 | N | Outstanding Actress in a Comedy Series | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Favorite Television Actress | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Favorite TV Comedy Actress | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Actress in a Series, Comedy or Musical | Ugly Betty (2006) (TV) | - |
| 2007 | W | Best Actress in a Series, Comedy or Musical | Ugly Betty (2006) (TV) | - |
| 2006 | N | Best Actress in a Series, Comedy or Musical | Ugly Betty (2006) (TV) | - |
| 2005 | N | Outstanding Actress in a Supporting Role, Comedy or Musical | The Sisterhood of the Traveling Pants (2005) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Outstanding Performance by a Female Actor in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2008 | N | Outstanding Performance by a Female Actor in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2008 | N | Outstanding Performance by an Ensemble in a Comedy Series | Ugly Betty (2006) (TV) | Vanessa Williams, Becki Newton, Christopher Gorham |
| 2007 | W | Outstanding Performance by a Female Actor in a Comedy Series | Ugly Betty (2006) (TV) | - |
| 2007 | N | Outstanding Performance by an Ensemble in a Comedy Series | Ugly Betty (2006) (TV) | Vanessa Williams, Ana Ortiz, Mark Indelicato |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2002 | W | Dramatic (For acting) | Real Women Have Curves (2002) | Lupe Ontiveros |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | Choice Comedy TV Actress | Superstore (2015) (TV) | - |
| 2009 | N | Choice TV Actress: Comedy | Ugly Betty (2006) (TV) | - |
| 2008 | N | Choice TV Actress: Comedy | Ugly Betty (2006) (TV) | - |
| 2007 | W | Choice TV: Breakout | Ugly Betty (2006) (TV) | - |
| 2007 | N | Choice TV Actress: Comedy | Ugly Betty (2006) (TV) | - |
| 2005 | N | Choice Movie Breakout Performance - Female | The Sisterhood of the Traveling Pants (2005) | - |
| 2005 | N | Choice Movie Hissy Fit | The Sisterhood of the Traveling Pants (2005) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2007 | N | Outstanding Individual Achievement in Comedy | Ugly Betty (2006) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | N | Best Performance in a Feature Film - Leading Young Actress | Real Women Have Curves (2002) | - |
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